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Further high-quality studies with commonly used antimicrobial agents for asymptomatic bacteriuria are needed to obtain better evidence. To assess the effects of different durations of treatment for asymptomatic bacteriuria in pregnancy.
Asymptomatic Bacteriuria Various antimicrobial drugs were used in the trials, e. Single-dose regimen of antibiotics may be less effective than the seven-day regimen. The objective of this review was to assess the advantages and disadvantages of treatments of different durations for asymptomatic bacteriuria in pregnancy.
In a comparison that did not reach statistical significance, single-dose regimen for asymptomatic bacteriuria appears to be less effective than four or seven days of treatment. All were comparisons of single-dose treatment with four- to seven-day treatments.
Eleven trials had been conducted in high-resource settings and two in low-resource ones. Nine studies participants were included in this review. No difference was seen when different drugs were compared.
Ten trials had compared the same antimicrobial agent administered in regimens of different durations, and the others had compared different medications.
Duration of treatment for asymptomatic bacteriuria during pregnancy 08 setembro The outcomes of interest were the development of symptomatic urinary tract infection, complications, death, adverse events, development of antibiotic resistance, bacteriological cure, and decline in kidney bacteriurai. Por que e como? An updated version of this systematic review has been published and can be found online at www. The objective of this Cochrane systematic review was to assess the effectiveness and safety of antibiotic treatment for asymptomatic bacteriuria in adults.
Skip to main content. There was no statistically significant difference in the recurrence of asymptomatic bacteriuria rate between treatment and control groups. Cochrane Database Syst Rev. According to the results of the studies included in this revision, authors have concluded that there is no clinical benefit in treating asymptomatic bacteriuria in adults. Asymptomatic bacteriuria is frequently detected in women aged up to 60 years, patients with diabetes and elderly patients.
The trials were generally of limited quality. However, this difference was not statistically singnificant and showed high heterogeneity. Findings of the review: Recursos Cochrane Review No. The incidence of symptomatic urinary tract infection, complications or death was similar between groups.
The benefit of antibiotic treatment for this condition is controversial. Randomised controlled trials RCTs and quasirandomised controlled trials bacteriugia antibiotics to placebo or no treatment for asymptomatic bacteriuria in adults were included.
Antibiotic use was significantly associated with bacteriological cure and an increase in minor adverse events. Randomized and quasi-randomized trials comparing antimicrobial therapeutic regimens that differed in duration particularly comparing single dose with longer duration regimens in pregnant women diagnosed with asymptomatic bacteriuria. Duration of treatment for asymptomatic bacteriuria during pregnancy Centro Hospitalar Lisboa Norte.
We will soon update the below RHL summary to reflect the updated findings of the systematic review. We included 13 studies, involving women.
Cochrane Database of Systematic ReviewsIssue Thirteen trials women comparing single-dose treatment with four- and seven-day treatments were included asslntomatica the review.
However, it is not clear whether single-dose therapy is as effective as longer conventional antibiotic treatment. You may also want to read Artigo RHL. Duration of treatment for asymptomatic bacteriuria during pregnancy. Slight differences were detected for preterm births and pyelonephritis although, apart from one trial, the sample size of the trials was inadequate. The rate of recurrence of asymptomatic bacteriuria was similar between different regimens used.
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